Panama from €495 Roundtrip: Air France & Air Europa Flights from Frankfurt

Escape to Central America with flights from Frankfurt to Panama City from just €495 roundtrip. Choose between Air France via Paris (CDG) or Air Europa via Madrid (MAD), with excellent availability from September through November 2026.

Panama City is a fascinating destination where modern skyscrapers meet colonial architecture and tropical scenery. It's also the perfect gateway to the Panama Canal, Caribbean beaches, Pacific coast islands, and the lush rainforests of Central America.

Highlights:

✔ Roundtrip fares from €495

✔ Flights from Frankfurt (FRA) to Panama City (PTY)

✔ Connections via Paris (CDG) with Air France or Madrid (MAD) with Air Europa

✔ Travel from September through November 2026

✔ Excellent availability throughout the autumn season

Example Dates:

1 September – 22 / 25 September / 3 October 2026

8 September – 1 October 2026

10 September – 4 October 2026

15 September – 1 / 3 / 4 October 2026

16 September – 7 October 2026

22 September – 6 / 13 October 2026

24 September – 6 / 11 / 22 October 2026

25 September – 11 / 16 / 18 October 2026

8 – 19 October 2026

9 – 18 October 2026

25 October – 8 / 12 / 14 November 2026

26 October – November (multiple return dates)

27 October – 8 / 14 / 19 / 20 November 2026

28 October – 7 / 9 / 14 / 17 / 20 November 2026

30 October – 7 / 8 / 14 / 15 / 20 / 23 November 2026

31 October – 7 / 8 / 11 / 14 / 16 / 20 / 21 / 23 November 2026

And many more dates are available throughout September, October, and November.